improve lives through RESEARCH

    Brain diseases, disorders, and injuries rob people of their human experience. You can fund research to improve prevention, diagnosis, and treatment of brain conditions. Whether it’s the ability to remember, communicate, move, think, or simply connect with family, each brain condition takes something from us. Give someone that piece of their humanity back.

Portraits of each scientist awarded an American Brain Foundation Cure One, Cure Many Award or Next Generation Research Grant in 2026.
Meet the Researchers Searching for Cures

In 2026, donor generosity has helped fund over $9 million in research grants to 20 research teams investigating the full spectrum of the brain. This is why the American Brain Foundation exists: to fund research that will improve lives.

Read more about these brilliant scientists
American Brain Foundation Global Ambassador and National Chair for Brain Health Advancement

Selma Blair

We are honored and thrilled to welcome iconic actress, author, and advocate Selma Blair as our Global Ambassador and National Chair for Brain Health Advancement.

In 2018, Selma publicly shared her diagnosis with relapsing multiple sclerosis or RMS, becoming a fearless voice for disability awareness. Selma’s story is a remarkable journey from symptoms to diagnosis, treatment, and advocacy.

OUR VISION

Life without brain disease

For 30 years, we have funded research across a broad spectrum of brain and nervous system diseases and disorders in the pursuit of improved treatments, prevention, and cures. We focus on the full spectrum of brain diseases and disorders because we believe that when we cure one disease, we will cure many. 

A family playing in a field.

$60M

We have granted nearly 60 million dollars to researchers

345

We have provided funding and scholarships to over 340 researchers

98%

Nearly 98% of our researchers have gone on to secure funding from the NIH and other national funders

45

45 scientists are actively undertaking innovative studies across multiple diseases

DRIVEN TO FIND A CURE

About the American Brain Foundation

We bring together the most respected researchers, brain disease organizations, and individual donors to achieve our shared goals.

Cure One, Cure Many
Brain Disease’s Impact
Funding Brain Disease Research
Get Involved
Cure One, Cure Many

Our whole-brain approach recognizes the interconnectedness of brain conditions and supports innovation through research by the best and brightest scientists. By examining the whole brain, we get the whole picture. When we cure one brain disease, we will cure many. 

Brain Disease’s Impact

There are over 1 billion people across the globe whose lives are impacted by brain diseases like multiple sclerosis, Alzheimer’s disease, Lewy body dementia, stroke, migraine, epilepsy, and more. Our goal is to bring that number to zero. 

Funding Brain Disease Research

Through programs like our Next Generation Research Grants and the Cure One Cure Many research award, we are committed to funding the innovative research of early-career and established investigators, encouraging a passion for research and laying the groundwork for the cures of tomorrow. 

Learn More
Get Involved

Together, we can outsmart brain disease. Make your donation today to help make life without brain disease a reality. 

Donate Now

Cure One, Cure Many Award

The American Brain Foundation’s Cure One, Cure Many Award supports breakthrough research in brain disease. The award provides large-scale, catalyst funding to the world’s top researchers who are pursuing the most innovative, cross-cutting approaches to finding diagnoses, treatments, and cures for brain disease. The award targets research topics that cut across multiple disease areas.

NEXT GENERATION RESEARCHERS

Working to Find Cures

The Next Generation Research Grants program funds and supports innovative investigations by the best and brightest early-career researchers working today to find the cures of tomorrow. We support their research across a broad spectrum of the brain and nervous system as they tackle things like identifying and treating ALS, developing treatments for Parkinson’s disease, predicting outcomes for TBI patients, and more. 

BRAIN DISEASES AND DISORDERS

Brain Diseases From A-Z

Brain conditions come in many different forms and go by many different names. They affect the lives of one in three people worldwide, in addition to the lives of their family, friends, and caregivers. Learn more about the diseases, disorders, and injuries that affect the brain and nervous system, including ALS, dementia, brain tumors, headache, stroke, and more.

Support Brain Research

We need your help to continue to fund brain research projects and find cures. Stand with us in the fight against brain diseases and disorders.

Together, we can build a future without brain disease.

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Blog

News and Articles

Discover the latest news in brain disease research, hear stories from people affected by brain disease and their caregivers, read up on brain disease-specific information, and more.

A cross-disciplinary medical team consulting on patient care for a brain tumor.

How Cross-Disciplinary Care Is Reshaping Brain Tumor Treatment

This is a guest post in partnership with Mayo Clinic. A brain tumor diagnosis changes everything in an instant.  For patients and families, the questions come all at once: Is it operable? How dangerous…
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An illustration of the connection between the brain and the gut on a blue background.

What Is the Gut–Brain Axis?

Your brain and digestive system are more connected than you might think. They send nerve signals back and forth, and this close relationship is crucial to human survival, well-being, and…
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Two photographs of Connie and an image of a brain scan.

Connie’s Story

When Connie visited the ER, the doctors dismissed her concerns as anxiety. It turned out she had a brain tumor that required immediate surgery. She was lucky to survive, but…
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Photographs of Raj, and her mother who experienced cerebral hypoxia and unresponsive wakefulness syndrome after failing to get enough oxygen during surgery.

Raj’s Story

Due to brain injuries from cerebral hypoxia, Raj’s mother was mostly unresponsive for forty years, since the day Raj was born. This deprived her of the opportunity to know her…
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An illustration of the brain within the head.

5 Things about the Brain You Learned in School

If you graduated from high school a while ago, it’s understandable that you may have forgotten about some of the things you learned about the brain in science classes over…
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A photograph of a woman with an illustration of a DNA helix faded behind her.

Managing Genetic Brain Disease Risk

Many brain diseases and disorders are caused or influenced by genetics. Genetic tests can confirm that individuals have a high risk of developing a serious brain condition, but until recently…
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A photograph of a couple sitting in bed, both scrolling on their phones.

Doomscrolling and Its Effects on the Brain

In an era when everyone is connected to online news and social media through smart phones, doomscrolling—or continuously absorbing distressing information—may seem unavoidable. However, exposure to constant negative stimuli can…
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A photograph of a man standing in the strong rays of the sun on a hot summer day.

Summer Heat and Its Effect on the Brain

Amplified by climate change, hot summer temperatures can have negative effects on your body, mental health, and physical brain. It can also make pre-existing brain conditions worse. With heat waves…
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A photograph of Selma Blair, American Brain Foundation Global Ambassador and National Chair for Brain Health Advancement.

Selma’s Story

Selma Blair is an iconic actress, author, and advocate whose impact spans film, television, fashion, and activism. In 2018, she publicly shared her diagnosis with relapsing multiple sclerosis or RMS, becoming…
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