What Is Cure One, Cure Many?

At the American Brain Foundation, the philosophy of “Cure One, Cure Many” drives our commitment to investing in research across the full spectrum of brain diseases and disorders.

But what exactly does it mean to
”Cure One, Cure Many?”

When we find the cure for one brain disease, we will find cures for many others.

The brain is a complex organ that serves many distinct, interrelated functions, from memory and thinking to coordinating complex muscle movements. And just as all parts of the brain are connected, so too are the 600+ brain diseases and disorders that impact millions of people worldwide every day.

“Cure One, Cure Many” reflects our belief that we will make a bigger impact by focusing research on these connections rather than on a single brain disease at a time. This approach gives us an edge in fighting brain disease, because it allows us to expand our understanding of how different diseases and brain functions are related, painting a broader picture of how the brain operates as a whole. Think about the difference between looking at a single point on a painting from an inch away vs. stepping back and taking in the whole canvas at once.

Just one discovery could create a ripple effect that impacts our understanding of many other related diseases, leading to better treatments, opportunities for earlier diagnosis, and cures. By investing in research across a range of diseases and disorders, we improve our chances of identifying these connections.

Types of Brain Disease

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Cerebrovascular Diseases

Neurodegenerative Disorders

Autoimmune Diseases

Seizure Disorders

Brain Trauma

Movement Disorders

Nerve and Muscle Disorders

Brain Tumor

Brain Disease Mechanisms

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Disorders of Metabolism

Disorders of Neuronal-Glial Interaction






That Can Lead
to Cures

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Migraine and Epilepsy

Alzheimer’s Disease, Parkinson’s Disease, and Lewy Body Dementia (LBD)

Neuroinflammation and Neurodegenerative Diseases

Jerry Mendell, MD

Shafali Jeste, MD, FAAN

Cure One, Cure Many Award for the Early Diagnosis of Lewy Body Dementia (LBD)

What Does

Cure One, Cure Many

Look Like in Action?

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Cure One, Cure Many: Connections Between Brain Diseases

Looking for ways to support brain disease research?
Investing in research across the whole brain requires continued support and dedication from donors like you.

With your help, life without 
 brain disease is possible.