Epilepsy affects 50 million people worldwide. Anti-seizure medications (ASMs) are successful, but side effects can decrease quality of life. Following a seizure-free period, many patients may consider discontinuing ASMs. Dr. Terman will study the effect of ASM discontinuation on seizure relapse risk, will and create an individualized risk calculator of seizure relapse for both discontinuation and continuation of ASMs. This research will help doctors and patients make better treatment decisions by estimating the risks and benefits of discontinuing anti-seizure medications.
This research is funded by the American Epilepsy Society, the Epilepsy Foundation, and American Brain Foundation, in collaboration with the American Academy of Neurology. Dr. Terman will conduct his research at the University of Michigan.