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Rowan Saloner, PhD

2024 Clinical Research Training Scholarship in FTD

 

Title/Institution: Clinical Neuropsychology Fellow, University of California, San Francisco

Project Title: “Large-scale biofluid proteomics to identify disease progression biomarkers in C9orf72 frontotemporal dementia”

Project Summary:  One of the most common causes of early onset dementia in people younger than 65 years is frontotemporal lobar degeneration (FTLD). However, there are currently no reliable biomarkers for FTLD, which makes it difficult to diagnose and treat. 

Dr. Saloner’s project will study a gene mutation called C9orf72 (C9) to help better understand the progression of FTLD and to identify potential biomarkers for this disease. Dr. Saloner will use advanced technology to analyze thousands of proteins in blood and spinal fluid from individuals with C9 mutations, comparing them with healthy and other mutation carriers. This research could lead to better diagnosis, treatment, and understanding of FTLD.