Unlocking the Secrets of the Immune System

Our immune system is a diverse and complex group of cells that patrol the body and eliminate infection and even cancer cells. Unfortunately, the immune system can sometimes become overly active, ramping up inflammation and targeting our own healthy tissue. When this happens the immune system can wreak havoc on the body, causing a diverse range of debilitating diseases, from inflammatory bowel disease to multiple sclerosis and even Alzheimer’s disease. Professor Steffen Jung and his team at the Weizmann Institute of Science hope to identify new ways to keep these rogue immune cells in check, which may offer new ways to treat autoimmune diseases of the gut and brain.

Steffen Jung MS & Autoimmune Disease March 1, 2018 at 6:19 pm

 

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Project Description

What we Know:
Over 5 million Americans suffer from Alzheimer’s disease, while 3 million have inflammatory bowel disease, and over 400,000 have multiple sclerosis. Other inflammatory diseases, such as asthma and arthritis, impact many more millions of American lives. These are grim figures in the face of a significant lack of effective treatments for some of these conditions. In addition, the immune system is complex and ever-changing, making it hard to study and control.

Improved Understanding to Help Find a Treatment:
An advantage in the study of inflammatory diseases, is that they share many of the same features and similar cells are involved. Professor Jung and his team are seeking to implement lab technology called quantitative realtime PCR (QuantStudio 6 Flex), which is vital for their immunological research. They will use this technology to study genetic changes in immune cell DNA under conditions of inflammation.

Our Plan to Help:
The American Brain Foundation, with your help, will give Professor Jung’s team the resources they need to make important new discoveries on the role of the immune system in a diverse range of devastating diseases. The findings Professor Jung and his team generate will not only help their own research, but may aid drug development efforts around the world, helping us get closer to finding effective treatments that may impact millions of Americans.

How You Can Help:
By donating to Professor Jung’s research through the American Brain Foundation, you would be directly contributing to the potential treatment of gut and brain disorders. Professor Jung hopes that by better understanding the changes that occur during inflammatory disease states, they can learn what causes them to occur, and may be able to stop them from debilitating and killing Americans suffering from Alzheimer’s, multiple sclerosis, or inflammatory bowel disease.

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