More than 40,000 women will die of breast cancer this year. Many of the most effective chemotherapy drugs for treating breast cancer cause serious side effects, including peripheral neuropathy, which causes numbness, pain and difficulty walking. Neuropathy is one of the most common reasons for stopping chemotherapy, potentially reducing the success of treatment. Neuropathy often drastically reduces quality of life. Drs Gordon Smith, Kelsey Juster-Switlyk and Summer Karafiath of the University of Utah plan to find out what causes neuropathy, so that we can prevent it and get patients the treatment they need and improve their quality of life.